Anti-HOXB7 Rabbit Polyclonal Antibody for WB, ELISA - P09629

Core Product Specifications and Parameters

Biological Background: HOXB7 Function and Localization

• HOXB7 (Homeobox protein Hox-B7) is also known as HHO.C1 or Hox-2C, encoded by the HOXB7 (formerly HOX2C) gene.
• It acts as a sequence-specific transcription factor that participates in a developmental regulatory network, providing cells with positional identities along the anterior-posterior body axis.
• The protein contains a conserved homeobox domain, enabling sequence-specific DNA binding and transcriptional regulation.
• HOXB7 belongs to the HOX gene family, a group of homeobox-containing genes that play fundamental roles in morphogenesis and cell differentiation.
• Subcellularly, HOXB7 localizes predominantly to the nucleus, consistent with its function as a transcription factor.
• According to UniProtKB annotations, HOXB7 has been identified in proteomics studies and is implicated in developmental processes and gene expression control.

Experimental Guidance and Technical Tips

• This antibody was raised against a recombinant protein corresponding to the N-terminal region (aa 1-120) of human HOXB7, which may recognize both full-length and truncated isoforms.
• For Western blotting, the predicted molecular weight of HOXB7 is approximately 24kDa; consider using a suitable protein ladder and loading controls to verify specificity.
• In ELISA applications, the antibody may be used for antigen capture or detection; optimize coating buffers and blocking conditions for best signal-to-noise ratio.
• Cross-reactivity with mouse HOXB7 has been noted, but performance may vary; validate the antibody in your specific sample type and experimental system.
• Since HOXB7 is a nuclear transcription factor, nuclear extracts may enhance detection sensitivity in tissue or cell lysate-based assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials, including validated antibody pairs and optimized polyclonal antibodies like this anti-HOXB7 product. For projects focusing on developmental biology or cancer research, CamelBio can streamline procurement of bulk ancillary reagents and facilitate sourcing of rare target raw materials, helping you move from concept to clinic efficiently.