Anti-HOOC4 Polyclonal Antibody for WB, ELISA - P09017

Core Product Specifications and Parameters

Biological Background: HOXC4 Function and Localization

• Homeobox protein Hox-C4 (also known as CP19 or Hox-3E) is a member of the HOXC family of homeodomain-containing transcription factors.
• It functions as a sequence-specific transcriptional regulator, conferring positional identity along the anterior-posterior body axis during development.
• HOXC4 contains a highly conserved homeobox domain that mediates DNA binding, enabling it to regulate target gene expression.
• The protein localizes to the nucleus, consistent with its role in transcriptional control.
• It is classified as a developmental protein and is part of the reference proteome for functional genomics studies.
• Post-translational modifications and tissue-specific expression patterns may modulate its activity, though details require further experimental validation.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 30-130, a region that includes part of the homeodomain; therefore, the antibody may detect both free and DNA-bound HOXC4.
• For Western blot, a band near 30 kDa is expected; however, consider potential isoforms or post-translational modifications that may shift the apparent molecular weight.
• This antibody has been validated by the supplier for WB and ELISA with human and mouse samples; for other species, cross-reactivity should be verified experimentally.
• Use appropriate nuclear extraction protocols to enrich the target protein and minimize background.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive range of IVD raw materials and technical support for diagnostic developers and research laboratories. Our catalog includes validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and custom sourcing for rare targets. With its critical role in development and transcription regulation, the HOXC4 antibody is a valuable tool for studying gene regulation networks and developmental biology.