Anti-HNRNPUL1 Rabbit Polyclonal Antibody for WB, ELISA - Q9BUJ2

Core Product Specifications and Parameters

Biological Background: HNRNPUL1 Function and Localization

• Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1), also known as E1BAP5, is an RNA-binding protein that belongs to the hnRNP family.
• Acts as a basic transcriptional regulator: represses basal transcription from various viral and cellular promoters, and activates glucocorticoid-responsive transcription when associated with BRD7.
• Plays a role in mRNA processing and transport, contributing to post-transcriptional regulation of gene expression.
• Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro, indicating strong affinity for GC-rich RNA sequences.
• Localizes primarily to the nucleus, consistent with its functions in transcription and mRNA metabolism.
• Subject to post-translational modifications including phosphorylation, methylation, isopeptide bond formation, and ubiquitination, which may regulate its activity and interactions.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant fragment spanning amino acids 209–410 of human HNRNPUL1; the antibody likely recognizes linear epitopes and is suitable for WB and ELISA applications.
• Verify antibody specificity in human and mouse samples; cross-reactivity with other species should be tested if required.
• For WB, expect a band range of 42–96 kDa due to potential isoforms or post-translational modifications; run appropriate molecular weight markers.
• Include proper positive and negative controls (e.g., knockdown or knockout cell lysates) to confirm detection of endogenous HNRNPUL1.
• Optimize antibody dilution for each application and sample type; titrate starting from a low concentration.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and research labs with a comprehensive portfolio of IVD raw materials, including validated antibodies, matched antibody pairs, and bulk ancillary reagents. This anti-HNRNPUL1 rabbit polyclonal antibody supports development of assays targeting transcription regulation, mRNA processing, and viral–host interaction pathways. For specialized projects requiring rare targets or custom antibody sourcing, CamelBio offers streamlined access from concept to clinic under one roof.