Anti-Hemopexin (HPX) Rabbit Monoclonal Antibody for WB, IF-P, IHC-P, ELISA - P02790

Core Product Specifications and Parameters

Biological Background: Hemopexin Function and Localization

• Hemopexin (HPX), also termed beta-1B-glycoprotein, is a secreted glycoprotein encoded by the HPX gene.
• It functions as a high-affinity heme-binding protein that transports heme to the liver for breakdown and iron recovery.
• After hepatic uptake, free hemopexin is recycled back to the circulation for subsequent rounds of heme scavenging.
• HPX is predominantly synthesized in the liver and secreted into plasma, consistent with its systemic heme-detoxifying role.
• The protein contains multiple disulfide bonds and glycosylation sites (Keywords: Disulfide bond, Glycoprotein).
• Hemopexin participates in metal-binding (iron) and host-virus interactions, highlighting its roles in iron homeostasis and innate immunity.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide corresponding to amino acids 363–462; thus the antibody may recognize both native and denatured forms, making it suitable for WB, IF-P, IHC-P, and ELISA.
• For WB, an expected band near 52 kDa should be observed; consider validating in liver-derived cell lines or tissue lysates.
• Cross-reactivity with rat enables multi-species studies; titrate and validate in the relevant sample system.
• Use appropriate positive and negative controls, especially when assessing heme-binding dynamics or secretion pathways.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a one-stop IVD raw-material partner supplying diagnostic manufacturers and labs with validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare target sourcing. This anti-Hemopexin rabbit monoclonal antibody supports heme transport and iron metabolism research, exemplifying our commitment to delivering high-quality reagents for your assay development needs. We offer flexible supply solutions—from research-grade to bulk production—to accelerate your projects from concept to clinic.