Anti-HAUS6 Polyclonal Antibody for WB and ELISA - Q7Z4H7

Core Product Specifications and Parameters

Biological Background: HAUS6 Function and Localization

• HAUS6 is a subunit of the HAUS augmin-like complex, which plays a crucial role in mitotic spindle assembly and centrosome integrity.
• The protein contributes to the completion of cytokinesis and the nucleation of microtubules from the spindle.
• HAUS6 promotes recruitment of NEDD1 and gamma-tubulin to the spindle, facilitating microtubule organization.
• It localizes predominantly to the cytoplasm, cytoskeleton, spindle, and centrosome during cell division.
• The protein is subject to phosphorylation and alternative splicing, as indicated by proteomics and structural studies.
• Aliases for HAUS6 include Dgt6 and FAM29A, reflecting its augmin complex membership and earlier provisional names.

Experimental Guidance and Technical Tips

• The immunogen used corresponds to an internal region (amino acids 676-955) of human HAUS6; the antibody may recognize full-length HAUS6 at the predicted molecular weight of ~109 kDa.
• For Western blot, consider using whole-cell lysates from human or mouse cell lines known to express HAUS6, and validate band specificity with appropriate controls.
• In ELISA applications, ensure the coating antigen matches the epitope region; titration experiments may help optimize working concentrations.
• Since the antibody is polyclonal, batch-to-batch variation can occur; validate each new lot in your assay system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers streamlined access to high-quality IVD raw materials, including this validated HAUS6 polyclonal antibody. Whether you need bulk supplies of detection reagents, monoclonal/polyclonal antibody pairs, or rare target sourcing for mitosis and centrosome research, our one-stop platform connects diagnostic and life science manufacturers with reliable, research-grade materials. Explore our full portfolio to accelerate your assay development from concept to clinic.