Anti-GTSF1 Polyclonal Antibody for WB, IF/ICC, ELISA - Q8WW33

Core Product Specifications and Parameters

Biological Background: GTSF1 Function and Localization

• GTSF1 (Gametocyte-specific factor 1), also known as FAM112B, is a zinc-finger protein.
• It is essential for spermatogenesis and male germ cell differentiation.
• GTSF1 suppresses retrotransposon transcription in male germ cells, preserving genomic integrity.
• Subcellular localization is predominantly cytoplasmic.
• The protein contains zinc-finger domains, indicating potential DNA/RNA-binding roles.
• Predicted molecular weight is approximately 19 kDa.
• Keywords: metal-binding, phosphoprotein, reference proteome, spermatogenesis.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant protein spanning the N-terminal region (aa 1-167). Validate antibody specificity using peptide blocking or knockout models.
• For Western blot, the predicted band is around 19 kDa. Use appropriate tissue lysates such as testis extracts.
• In IF/ICC, cytoplasmic staining is expected. Optimize permeabilization conditions.
• ELISA: Ensure the coating antigen matches the immunogen region for optimal detection.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive supply chain for IVD raw materials, providing validated antibodies, bulk reagents, and custom sourcing for rare targets like GTSF1. Our polyclonal antibodies support reproductive biology and spermatogenesis research. From antibody pairs to technical consultation, CamelBio bridges your diagnostic development from concept to clinic.