Anti-GTSE1 Polyclonal Antibody for WB and ELISA - Q9NYZ3

Core Product Specifications and Parameters

Biological Background: GTSE1 Function and Localization

• GTSE1, also known as Protein B99 homolog, is a G2 and S phase-expressed protein encoded by the GTSE1 gene in humans.
• It is implicated in p53-induced cell cycle arrest at the G2/M phase by interfering with microtubule rearrangements required for mitosis entry.
• Overexpression of GTSE1 delays progression through the G2/M phase of the cell cycle.
• The protein localizes to the cytoplasm and associates with the cytoskeleton, specifically microtubules.
• GTSE1 is a phosphoprotein, suggesting regulation by phosphorylation.
• The full-length protein has a molecular weight of approximately 78.5 kDa (UniProt), with observed bands around 77 kDa.

Experimental Guidance and Technical Tips

• For Western blotting, consider using whole cell lysates from human, mouse, or rat cell lines; a band around 77 kDa may be detected.
• Validate antibody specificity in the relevant sample system, as performance can vary with experimental conditions.
• For ELISA applications, the antibody may be tested with purified recombinant protein or peptide antigens.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and researchers streamlined access to IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. For GTSE1 cell cycle research, we can support your projects with high-quality reagents and rare target sourcing, helping bridge the gap from discovery to clinical application.