Anti-GSTO2 Polyclonal Antibody for IF/ICC and ELISA - Q9H4Y5

Core Product Specifications and Parameters

Biological Background: GSTO2 Function and Localization

• Glutathione S-transferase omega-2 (GSTO2), also known as GSTO 2-2, is a member of the omega class of glutathione S-transferases.
• GSTO2 exhibits glutathione-dependent thiol transferase activity and high dehydroascorbate reductase activity, potentially contributing to the recycling of ascorbic acid (vitamin C).
• The enzyme participates in the biotransformation of inorganic arsenic by reducing monomethylarsonic acid (MMA(V)), playing a role in cellular detoxification pathways.
• According to UniProt, GSTO2 is expressed in a range of tissues, with strongest expression in the testis and also detected in liver, kidney, skeletal muscle, and prostate.
• The protein is annotated with keywords including oxidoreductase, transferase, and alternative splicing, and its 3D structure has been experimentally determined.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 124–243 (C-terminal region) of human GSTO2, which may provide specific recognition in immunoassays.
• For immunofluorescence/immunocytochemistry, optimize permeabilization and fixation conditions for the target cell type.
• In ELISA applications, validate the antibody using recombinant or native GSTO2 in the appropriate sample matrix.
• The predicted molecular weight is approximately 28 kDa; confirm band size if adapting the antibody for Western blotting, though the current validation is for IF/ICC and ELISA.
• As a polyclonal antibody, lot-to-lot variability may occur; consider including internal controls in critical experiments.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one‑stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti‑GSTO2 polyclonal antibody supports investigations into glutathione metabolism, oxidative stress, and arsenic detoxification. Beyond individual antibodies, we offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare‑target raw‑material sourcing to accelerate your assay development.