Anti-GSTM5 Rabbit Polyclonal Antibody for WB, ELISA - P46439

Core Product Specifications and Parameters

Biological Background: GSTM5 Function and Localization

• GSTM5 (glutathione S-transferase Mu 5) is a member of the GST mu class, encoded by the GSTM5 gene.
• It catalyzes the conjugation of reduced glutathione to a variety of exogenous and endogenous hydrophobic electrophiles, playing a key role in detoxification pathways.
• Known also as GSTM5-5 or GST class-mu 5, it belongs to a family of cytosolic transferases involved in cellular protection.
• Subcellular localization is cytoplasmic, consistent with its function in metabolizing electrophilic compounds.
• Key structural features include a molecular weight of approximately 25.7 kDa (UniProt) and conserved GST domains.
• This protein is classified under transferase activity and is part of the reference proteome.

Experimental Guidance and Technical Tips

• The immunogen is designed from the C-terminal region (amino acids 100 to the C-terminus); verify that the target epitope is accessible in your sample preparation and not masked by post-translational modifications.
• For Western blotting, a specific band around 26 kDa is expected. Validate the antibody in your relevant sample system (human, mouse, or rat) and consider appropriate loading controls.
• This antibody is suitable for ELISA; optimization of coating antigen concentration and antibody dilution is recommended for best signal-to-noise ratio.
• Due to polyclonal origin, lot-to-lot consistency may vary; pre-screen each new lot if quantitative data reproducibility is critical.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with streamlined, one-stop access to a comprehensive portfolio of IVD raw materials. This GSTM5-targeting antibody supports assay development in toxicology and detoxification biomarker research. Beyond individual antibodies, we supply validated antibody pairs, optimized monoclonal/polyclonal reagents, and bulk ancillary materials—helping you bridge concept-to-clinic sourcing gaps efficiently.