Anti-GLUT3/SLC2A3 Rabbit Monoclonal Antibody for WB, IP, ELISA - P11169

Core Product Specifications and Parameters

Biological Background: GLUT3/SLC2A3 Function and Localization

• GLUT3, also known as solute carrier family 2, facilitated glucose transporter member 3, is encoded by the SLC2A3 gene. It mediates facilitative glucose transport across the cell membrane and can also transport other monosaccharides (PubMed:26176916, PubMed:32860739, PubMed:9477959). Related references: PMID:26176916, PMID:32860739, PMID:9477959
• Substrate specificity includes glucose, 2-deoxyglucose, galactose, mannose, xylose, and fucose, but not fructose (PubMed:26176916, PubMed:9477959). Related references: PMID:26176916, PMID:9477959
• Localized primarily at the cell membrane, with detection in the perikaryon and cell projections.
• Highly expressed in the brain (PubMed:8457197) and widely expressed in other tissues. Related references: PMID:8457197
• Undergoes glycosylation and phosphorylation, as indicated by the presence of glycoprotein and phosphoprotein keywords.
• Plays an essential role in mesendoderm differentiation (By similarity).
• Belongs to the major facilitator superfamily and contains 12 predicted transmembrane helices, characteristic of sugar transporters.

Experimental Guidance and Technical Tips

• For Western blotting, the predicted molecular weight of GLUT3 is approximately 54 kDa. Validate the antibody with positive and negative control lysates and consider using optimized blocking and detection conditions.
• For immunoprecipitation, optimize antibody concentration and use gentle lysis buffers to preserve native protein interactions. Confirm specificity with appropriate controls.
• For ELISA, this antibody may be used as a capture or detection reagent. Pair with a matched antibody for sandwich ELISA and validate using recombinant GLUT3 protein or relevant cell lysates.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with one-stop access to IVD raw materials, including this anti-GLUT3/SLC2A3 monoclonal antibody. We offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and can assist in sourcing rare-target raw materials for metabolic and neurological research applications. Let CamelBio streamline your procurement from discovery to clinic.