Anti-GLP2R Monoclonal Antibody for WB and ELISA - O95838

Core Product Specifications and Parameters

Biological Background: GLP2R Function and Localization

• GLP2R is the receptor for glucagon-like peptide 2 (GLP-2).
• It is a class B G protein-coupled receptor (GPCR) with seven transmembrane helices.
• Upon GLP-2 binding, the receptor activates heterotrimeric G proteins, primarily Gαs, which stimulate adenylyl cyclase and increase intracellular cAMP levels.
• The receptor is localized to the cell membrane.
• Post-translational modifications include disulfide bond formation and glycosylation, which are important for proper folding and function.
• GLP2R has been identified in proteomic studies.
• It belongs to the reference proteome set.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein corresponding to the C-terminal region (amino acids 460-553) of human GLP2R. This region may be intracellular; consider its accessibility for applications requiring native conformation.
• This rabbit monoclonal antibody is validated for Western blot (WB) and ELISA. For WB, a band at approximately 63 kDa is expected; validate in your sample system with appropriate controls.
• Cross-reactivity is reported for human, mouse, and rat. Sequence alignment between species can help predict reactivity in other species.
• For ELISA, titrate the antibody and optimize blocking conditions to reduce background.
• Store at recommended temperature upon receipt; shipped on ice bags.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing partner for IVD raw materials, providing researchers and manufacturers with high-quality monoclonal and polyclonal antibodies, recombinant proteins, and ancillary reagents. The GLP2R antibody supports gastrointestinal and metabolic disease research, and we can also supply matched antibody pairs, optimized clones, and bulk quantities to accelerate your assay development. From early-stage concept to clinical application, trust CamelBio to bridge your raw-material needs.