Anti-GIP Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - P09681

Core Product Specifications and Parameters

Biological Background: Gastric inhibitory polypeptide (GIP) Function and Localization

• GIP (Gastric inhibitory polypeptide), also referred to as glucose-dependent insulinotropic polypeptide, is a 17 kDa incretin hormone.
• It is a potent stimulator of glucose-dependent insulin secretion from pancreatic beta cells.
• GIP plays a relatively modest role in inhibiting gastric acid secretion.
• The protein is secreted and undergoes proteolytic processing, including cleavage on pair of basic residues.
• Keywords associated with GIP include hormone, secreted, signal, and reference proteome, among others.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein corresponding to amino acids 22–153 of human GIP, covering the mature peptide region for effective detection.
• For WB, expect a band at ~17 kDa; optimize reducing conditions and include a positive control expressing GIP.
• In IHC-P, tissue sections from human, mouse, or rat intestine or pancreas are suitable starting points to confirm reactivity.
• For ELISA, the polyclonal antibody can serve as capture or detection reagent; titrate to determine optimal working dilutions.
• Since GIP is secreted, sample handling may require protease inhibitors or concentration steps to maintain integrity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic and research laboratories by providing validated IVD raw materials, including this anti-GIP polyclonal antibody for diabetes and metabolic disorder studies. As a one-stop sourcing partner, we offer tailored antibody pairs, bulk reagents, and technical consulting to accelerate your assay development from concept to clinic.