Anti-GIMAP1 Polyclonal Antibody for WB, ELISA - Q8WWP7

Core Product Specifications and Parameters

Biological Background: GIMAP1 Function and Localization

• GIMAP1 (GTPase IMAP family member 1) is an immunity-associated protein also referred to as IMAP1, HIMAP1, or IMAP38.
• It functions in lymphocyte biology, potentially regulating survival, and is necessary for maintaining normal levels of mature T and B cells.
• At the subcellular level, GIMAP1 resides on endoplasmic reticulum and Golgi apparatus membranes.
• Tissue expression is predominantly in the spleen and lymph nodes, with detection in T-cells.
• GIMAP1 is a transmembrane GTP-binding protein, featuring transmembrane helices and nucleotide-binding domains.
• Additional characterization includes available 3D structural data and proteomic identification.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 140-280 of human GIMAP1, suggesting recognition of epitopes in this central region; consider this when designing epitope-mapping experiments.
• For Western blotting, expect a band near 34 kDa; use positive controls such as spleen or lymphocyte lysates to confirm specificity.
• For ELISA, validate binding using recombinant GIMAP1 protein or cell-derived material; the reported cross-reactivity with rat allows potential application in rodent studies.
• As a polyclonal antibody, lot-to-lot consistency may vary; always titrate and optimize working dilutions for your specific assay conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and research institutes a reliable, one-stop channel for IVD raw materials, including this anti-GIMAP1 polyclonal antibody for lymphocyte and GTPase research. Beyond individual reagents, we supply validated antibody pairs, bulk ancillary reagents, and custom sourcing for rare targets, supporting your workflow from concept to clinic.