Anti-FOXS1 Polyclonal Antibody for WB, ELISA - O43638

Core Product Specifications and Parameters

Biological Background: FOXS1 Function and Localization

• FOXS1 (Forkhead box protein S1) is a transcription factor, also known as FKHL18 or FREAC10, belonging to the forkhead family of DNA-binding proteins.
• It functions as a transcriptional repressor, downregulating the expression of target genes such as FASLG, FOXO3, and FOXO4.
• FOXS1 may play a role in the organization of the testicular vasculature, as suggested by similarity studies.
• The protein is primarily localized in the nucleus where it exerts its transcriptional regulatory functions.
• FOXS1 is a DNA-binding protein with a forkhead domain, classified under the reference proteome and identified in proteomics studies.
• No information available about post-translational modifications or tissue-specific expression from the provided record.

Experimental Guidance and Technical Tips

• For Western blotting, the predicted molecular weight of FOXS1 is approximately 35 kDa. Consider using appropriate molecular weight markers and verify band specificity using relevant positive and negative controls.
• In ELISA, the antibody may be used for indirect detection; optimization of coating antigen concentration and antibody dilution is recommended.
• Given the rabbit polyclonal nature, this antibody may recognize multiple epitopes; consider validating specificity in the target species (human, rat) before critical experiments.
• Since the immunogen covers a specific region (aa 121-330), this antibody may react with isoforms containing that region; cross-reactivity with other forkhead proteins is possible and should be assessed.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti-FOXS1 polyclonal antibody is part of our extensive portfolio supporting transcription factor research and vascular biology. We offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing—all designed to streamline your assay development and production workflows.