Anti-FOXQ1 Rabbit Polyclonal Antibody for IHC-P, ELISA - Q9C009

Core Product Specifications and Parameters

Biological Background: FOXQ1 Function and Localization

• FOXQ1 (Forkhead box protein Q1, also known as HNF-3/forkhead-like protein 1 or HFH1) is a transcription factor encoded by the FOXQ1 gene (Gene ID: 94234).
• It belongs to the forkhead box (FOX) family, characterized by a conserved DNA-binding forkhead domain.
• FOXQ1 plays a critical role in hair follicle differentiation, contributing to the regulation of epithelial development.
• The protein is expressed predominantly in the stomach, trachea, bladder, and salivary gland, indicating tissue-specific regulatory roles.
• Subcellularly, FOXQ1 localizes to the nucleus, consistent with its function as a transcription factor.
• FOXQ1 is classified as a DNA-binding protein involved in transcription regulation.

Experimental Guidance and Technical Tips

• For IHC-P, consider optimizing antigen retrieval conditions and antibody dilution using positive control tissues such as stomach, trachea, bladder, or salivary gland, where FOXQ1 expression is high.
• In ELISA, use immobilized recombinant FOXQ1 protein or peptide as the coating antigen; validate the assay by including appropriate controls and assessing linearity and specificity.
• The immunogen is an N-terminal peptide (amino acids 1-100); confirm that the epitope is accessible in your experimental context, particularly when detecting endogenous protein or in paraffin-embedded sections.
• As a polyclonal antibody, lot-to-lot consistency may vary; we recommend validating each new lot in your specific application and model system.
• The antibody has been confirmed to react with human FOXQ1; cross-reactivity with other species is not characterized, so test in the appropriate species if necessary.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your integrated partner for IVD raw material sourcing, offering a comprehensive portfolio that includes validated antibodies, antigens, and ancillary reagents to streamline your assay development. This FOXQ1 rabbit polyclonal antibody is part of our collection supporting dermatology and developmental biology research. Whether you need customized bulk orders, rare target sourcing, or technical consultation, CamelBio bridges the gap from concept to clinical application with reliable supply and expert support.