Anti-FGF6 Polyclonal Antibody for WB, ELISA - P10767

Core Product Specifications and Parameters

Biological Background: FGF6 Function and Localization

• Fibroblast growth factor 6 (FGF6), also known as HST-2 or HBGF-6, is a secreted heparin-binding growth factor belonging to the fibroblast growth factor family.
• It plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis, and myogenesis, and is required for normal muscle regeneration.
• FGF6 is proteolytically processed and secreted into the extracellular space, where it interacts with cell-surface receptors.
• The protein is classified under multiple keywords including angiogenesis, developmental protein, differentiation, mitogen, and proto-oncogene, reflecting its diverse biological functions.
• Tissue expression is observed in leukemia cell lines with platelet/megakaryocytic differentiation potential.
• FGF6 contains a signal peptide, is glycosylated, and has a predicted molecular weight of approximately 23 kDa.

Experimental Guidance and Technical Tips

• This antibody was raised against a synthetic peptide within the N-terminal region (aa 1-100) of human FGF6. Since FGF6 is a secreted protein, sample preparation (e.g., cell lysates vs. conditioned medium) should be carefully considered.
• The predicted molecular weight of FGF6 is ~23 kDa; however, post-translational modifications may cause slight shifts in migration on SDS-PAGE. Validate the band pattern in your experimental system.
• For Western blotting, ensure proper blocking and use appropriate secondary antibodies. The antibody cross-reacts with mouse and rat, facilitating research across species.
• For ELISA applications, the antibody can be used as a detection reagent; optimal working dilutions should be determined by end users.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and research labs with a comprehensive portfolio of IVD raw materials, including validated polyclonal antibodies like this anti-FGF6 antibody for growth factor and angiogenesis studies. Beyond individual reagents, we offer one-stop access to optimized antibody pairs, bulk ancillary reagents, and custom sourcing for rare targets, supporting your workflow from early development to clinical application.