Anti-FGF10 Rabbit Polyclonal Antibody for WB, ELISA - O15520

Core Product Specifications and Parameters

Biological Background: FGF10 Function and Localization

• FGF10, also known as keratinocyte growth factor 2, is a secreted glycoprotein belonging to the fibroblast growth factor family.
• It plays a critical role in embryonic development, regulating cell proliferation and differentiation.
• Essential for normal branching morphogenesis, particularly in lung, limb, and organ development.
• May participate in wound healing processes.
• Subcellular location: Secreted (extracellular space).
• Associated disease variants include ectodermal dysplasia and lacrimo-auriculo-dento-digital syndrome.
• Contains a signal peptide and is glycosylated, with a calculated molecular weight of approximately 23.4 kDa.
• The protein is identified through reference proteomics and has a known 3D structure.

Experimental Guidance and Technical Tips

• The immunogen spans the core FGF domain (amino acids 40–208), suggesting suitability for detecting both full-length and processed forms in WB.
• For Western blot, consider using reducing SDS-PAGE and standard transfer conditions; validate the antibody in your relevant sample system (human, mouse, or rat).
• For ELISA, optimize the coating antigen concentration and antibody dilution for either sandwich or indirect formats.
• Due to confirmed cross-reactivity with mouse and rat, this antibody can be used for comparative studies in rodent models.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and researchers with high-quality IVD raw materials, from validated polyclonal antibodies like this FGF10 pAb to optimized antibody pairs and ancillary reagents. Whether you need bulk quantities or rare target sourcing for developmental biology and oncology research, CamelBio streamlines your supply chain from concept to clinic.