Anti-Fetuin A/AHSG Monoclonal Antibody for WB, ELISA - P02765

Core Product Specifications and Parameters

Biological Background: Fetuin A/AHSG Function and Localization

• Fetuin A/AHSG (Alpha-2-HS-glycoprotein) is a secreted plasma protein, also known as Fetuin-A, synthesized primarily in the liver.
• It promotes endocytosis and possesses opsonic properties, enhancing phagocytosis of certain particles.
• Demonstrates affinity for calcium and barium ions, influencing the mineral phase of bone and calcium homeostasis.
• Selectively concentrated in bone matrix and found in dentin at higher levels than other plasma proteins, contributing to mineralized tissue biology.
• The mature protein undergoes post-translational modifications including disulfide bond formation, glycosylation, and phosphorylation, as indicated by its keyword annotations.
• Associated with mineral balance and implicated in disease variants, although functional details of variants remain to be fully characterized.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a synthetic peptide from the N-terminal region (amino acids 1–100) of human Fetuin A/AHSG, suggesting reactivity with the full-length protein and potential recognition of processed or cleaved forms containing this epitope.
• For Western blot, the predicted molecular weight is ~39 kDa; however, due to glycosylation, the observed band may appear at a higher molecular weight. Consider using a deglycosylation step if a precise band size is critical.
• In ELISA, this antibody may be employed as a capture or detection reagent for quantifying Fetuin A/AHSG in human plasma or serum samples. Validate the antibody’s performance in your specific sample matrix and application context.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This Fetuin A/AHSG antibody supports research into bone metabolism, mineral balance, and plasma protein function. CamelBio offers validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing to accelerate your assay development.