Anti-FAM98A Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q8NCA5

Core Product Specifications and Parameters

Biological Background: FAM98A Function and Localization

• FAM98A is a protein of approximately 55 kDa, identified as part of the human reference proteome and characterized by proteomics approaches.
• It functions as a positive regulator of PRMT1-induced protein arginine methylation, a post-translational modification involved in various cellular processes. Related references: PMID:28040436
• FAM98A is involved in skeletal homeostasis, contributing to lysosome peripheral distribution and ruffled border formation in osteoclasts, which are critical for bone resorption (By similarity).
• At the tissue level, FAM98A is strongly expressed in colorectal cancer cells and tissues compared to normal colon, suggesting a potential role in cancer biology. Related references: PMID:28040436

Experimental Guidance and Technical Tips

• The immunogen covers the N-terminal region (amino acids 1‑220) of human FAM98A; consider this when assessing potential isoform recognition or cross‑reactivity in other species.
• For WB, the predicted molecular weight is ~55 kDa; use appropriate positive and negative controls to validate band specificity.
• For IHC‑P, optimize antigen retrieval conditions and primary antibody dilution based on the tissue type and fixation method.
• For ELISA, evaluate direct or indirect coating strategies and titrate the antibody concentration against the target antigen or immunogen.
• Cross‑reactivity with mouse and rat is expected; verify sequence conservation around the immunogen region to interpret staining patterns.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with a comprehensive range of IVD raw materials, including validated polyclonal antibodies like this anti‑FAM98A antibody, supporting studies on arginine methylation and skeletal biology. We offer access to optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare‑target raw‑material sourcing to streamline your assay development and production. Our one‑stop supply model helps you move efficiently from target identification to diagnostic application.