Anti-FAM3D Rabbit Polyclonal Antibody (pAb) for WB, IHC-P, IF/ICC, ELISA - Q96BQ1

Core Product Specifications and Parameters

Biological Background: FAM3D Function and Localization

• FAM3D, also known as EF7 or OIT1, is a member of the FAM3 family of cytokine-like proteins.
• It is a secreted glycoprotein, as indicated by its signal peptide and the presence of disulfide bonds, suggesting a role in extracellular signaling.
• FAM3D is predicted to have lectin-like properties based on sequence analysis.
• The protein is abundantly expressed in the placenta and at lower levels in the small intestine, indicating tissue-specific functions.
• Its molecular weight is approximately 25 kDa, consistent with the predicted mass of the mature peptide after signal peptide cleavage.
• FAM3D may function in immune modulation or cell adhesion, given its cytokine-like and potential lectin activities, though precise functions require further study.

Experimental Guidance and Technical Tips

• For Western blot, a band at ~25 kDa may be observed; note that glycosylation could result in a slightly higher apparent molecular weight.
• In immunohistochemistry (paraffin-embedded tissues), antigen retrieval may be required; validate in appropriate positive controls such as placenta.
• The polyclonal nature of this antibody may enhance sensitivity in ELISA applications.
• When using immunofluorescence, fixative choice and permeabilization conditions should be optimized for secreted protein detection.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials, including validated antibody pairs, monoclonal and polyclonal antibodies, and bulk ancillary reagents. This anti-FAM3D rabbit polyclonal antibody is suited for studies in reproductive biology and cytokine signaling. For custom or large-volume sourcing of rare targets, contact our team.