Anti-FAM3A Polyclonal Antibody for WB, IHC-P, ELISA - P98173

Core Product Specifications and Parameters

Biological Background: FAM3A Function and Localization

• FAM3A (Family with sequence similarity 3 member A) is also known as cytokine-like protein 2-19.
• It is a secreted protein that may act as a defensin against invading fungal microorganisms.
• FAM3A is widely expressed, with similar levels detected in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle, and heart.
• The protein contains a signal peptide, disulfide bonds, and a lectin domain, suggesting roles in carbohydrate binding and immune defense.
• Alternative splicing gives rise to multiple transcript variants, though their functional significance remains unclear.
• FAM3A belongs to the FAM3 family of cytokine-like proteins, which are structurally related to classical cytokines and growth factors.

Experimental Guidance and Technical Tips

• The immunogen (aa 34–230) targets the mature protein after signal peptide cleavage, making it suitable for detecting the secreted form.
• In WB, a specific band around 25 kDa is expected under reducing conditions; use a positive control such as human testis or pancreas lysate.
• For IHC-P, test antigen retrieval protocols and include tissue sections with known FAM3A expression (e.g., testis, pancreas).
• In direct or indirect ELISA, the antibody can be used as a capture or detection reagent; pairing with another FAM3A antibody may improve sensitivity in sandwich formats.
• As a polyclonal antibody, optimal working dilutions should be determined experimentally for each application and sample type.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a trusted one-stop provider of IVD raw materials, offering validated antibodies, recombinant proteins, and ancillary reagents for diagnostic development. Our portfolio supports FAM3A research and assay design, with access to optimized monoclonal and polyclonal antibodies, bulk reagents, and rare target sourcing. From concept to clinic, CamelBio streamlines your supply chain and technical needs.