Anti-FAM3A Monoclonal Antibody for WB, IHC-P, ELISA - P98173

Core Product Specifications and Parameters

Biological Background: FAM3A Function and Localization

• Protein FAM3A (also known as cytokine-like protein 2-19) is a secreted protein belonging to the FAM3 family, containing an N-terminal signal peptide.
• Its primary reported function is as a defensin, contributing to innate immunity against fungal microorganisms.
• FAM3A is broadly expressed across multiple tissues, including testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle, and heart.
• The protein is predicted to contain a lectin-like domain, as indicated by its keyword classification, and its structure is stabilized by disulfide bonds.
• Alternative splicing of the FAM3A gene generates multiple transcript variants, suggesting regulatory complexity.

Experimental Guidance and Technical Tips

• For Western blot (WB), a specific band at approximately 25 kDa is expected under reducing conditions; consider using positive control lysates from tissues with high FAM3A expression.
• In immunohistochemistry (IHC-P), antigen retrieval methods may be required; validate staining in relevant tissue sections such as pancreas or adrenal.
• The antibody is suitable for sandwich ELISA applications; optimize pairing with a matched detection antibody for best sensitivity.
• Since the immunogen covers amino acids 34-230, the antibody likely recognizes the mature secreted form of FAM3A; validate in the appropriate sample system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio specializes in providing validated IVD raw materials, offering one-stop access to high-quality antibodies, antigen pairs, and bulk reagents. This FAM3A rabbit monoclonal antibody supports defensin and fungal immunity research, and we can supply auxiliary reagents such as recombinant FAM3A protein and matched detection antibodies. For diagnostic manufacturers, CamelBio also sources rare targets and custom bulk production, streamlining your development from concept to clinic.