Anti-FAM160B2 Polyclonal Antibody for WB, ELISA - Q86V87

Core Product Specifications and Parameters

Biological Background: FAM160B2 Function and Localization

• FAM160B2 encodes the FHF complex subunit HOOK-interacting protein 2B (FHIP2B), also designated retinoic acid-induced protein 16 (RAI16).
• It is capable of activating MAPK/ERK and TGFβ signaling pathways, as shown in functional studies. Related references: PMID:22971576
• The protein plays a role in cell proliferation, supported by experimental evidence. Related references: PMID:22971576
• FAM160B2 may regulate genes involved in intestinal barrier function and immunoprotective inflammation, based on sequence similarity evidence.
• According to UniProt tissue specificity data, FAM160B2 is expressed in liver.
• It is included in proteomics identification databases and the reference proteome set.

Experimental Guidance and Technical Tips

• The antibody's immunogen is a synthetic peptide spanning amino acids 420-520 of human FAM160B2, which may contribute to specific detection in immunoassays.
• For Western blot, consider using whole cell lysates from human, mouse, or rat tissues/cells; a band around 82 kDa is anticipated.
• In ELISA applications, validation with appropriate peptide or recombinant protein standards is recommended to determine optimal conditions.
• Given cross-reactivity with mouse and rat, the antibody can be utilized in comparative studies across species.
• Optimal working dilutions and conditions should be determined empirically by the end user.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a one-stop sourcing solution for IVD raw materials, supporting diagnostic manufacturers and research labs from early development to clinical application. This FAM160B2 antibody is designed for studies in cell signaling and proliferative pathways. In addition to a wide range of validated antibodies, CamelBio offers optimized antibody pairs, bulk ancillary reagents, and custom sourcing services for rare or emerging targets, ensuring streamlined access to critical reagents.