Anti-FAM155B Rabbit Polyclonal Antibody for WB, ELISA - O75949

Core Product Specifications and Parameters

Biological Background: NALCN channel auxiliary factor 2 Function and Localization

• FAM155B, also known as NALF2, TED, or TMEM28, encodes the NALCN channel auxiliary factor 2.
• It is a probable component of the NALCN channel complex, which regulates the resting membrane potential and controls neuronal excitability.
• Localized to the cell membrane, consistent with its role as a transmembrane channel auxiliary factor.
• Contains predicted transmembrane helices, indicating multiple membrane-spanning domains.
• Classified as a glycoprotein and a reference proteome member, identified in mass spectrometry-based proteomics studies.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide from the C-terminal region (aa 400-472). When designing experiments, note that this epitope may recognize specific isoforms or cleavage products.
• For Western blotting, consider using appropriate positive controls such as neuronal cell lines, as FAM155B is implicated in neuronal excitability.
• This antibody shows cross-reactivity with mouse and rat, making it suitable for studies in rodent models, but always validate in your target tissue.
• For ELISA applications, optimization of coating antigen and detection conditions is recommended.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This FAM155B antibody supports neuroscience research and ion channel studies. We also offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing.