Anti-FAM127B Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q9BWD3

Core Product Specifications and Parameters

Biological Background: FAM127B Function and Localization

• FAM127B (also designated RTL8A, CXX1B, MAR8A, SIRH6) is a human protein encoded by the RTL8A gene, classified as a retrotransposon Gag-like protein 8A (UniProt Q9BWD3).
• It is annotated as a mammalian retrotransposon-derived protein, suggesting an evolutionary origin from ancient retrotransposon sequences.
• The protein is composed of 113 amino acids with a predicted molecular weight of approximately 13.2 kDa (UniProt entry), consistent with the observed ~13 kDa band.
• UniProt lists the protein under keywords "Proteomics identification" and "Reference proteome," indicating high-confidence protein-level evidence and inclusion in the standard human proteome.
• Currently, the specific cellular function, subcellular localization, and tissue distribution of FAM127B remain poorly characterized in the scientific literature.
• Sequence homology between human and mouse FAM127B is supported by antibody cross-reactivity, implying conserved structural motifs across these species.

Experimental Guidance and Technical Tips

• The immunogen used (recombinant full-length protein) provides broad epitope coverage, making it suitable for detecting both native and denatured forms of FAM127B in techniques like WB and IF/ICC.
• For ELISA, employing the recombinant immunogen as a coating antigen or standard can assist in quantification and assay validation.
• As the antibody shows reactivity to human and mouse, it is important to confirm its performance in the specific sample matrix and species of interest through proper positive and negative controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is dedicated to supporting IVD researchers and manufacturers with comprehensive raw-material solutions, from concept to clinical application. For FAM127B and other retrotransposon-related targets, we provide validated antibodies, recombinant proteins, and assay-matched ancillary reagents in bulk. Let us help you accelerate your diagnostic development with reliable, one-stop sourcing for both common and rare protein targets.