Anti-FAM127A/RTL8C Polyclonal Antibody for WB and ELISA - A6ZKI3

Core Product Specifications and Parameters

Biological Background: Retrotransposon Gag-like protein 8C Function and Localization

• Known as Retrotransposon Gag-like protein 8C (RTL8C), also referred to as Mammalian retrotransposon derived protein 8C.
• Encoded by the RTL8C gene (aliases: CXX1, FAM127A, MAR8, MAR8C, MART8) located on chromosome X.
• Identified in high-throughput proteomics screens, supporting its endogenous expression at the protein level.
• Designated as a 'Reference proteome' component, indicating its inclusion in the canonical human protein set.
• Belongs to the retrotransposon Gag-like protein family, characterized by similarity to retroviral Gag proteins.
• Alternative names include CXX1, Mar8, MAR8C, Mart8, SIRH5, and MART8C; some reflect its chromosomal location or retrotransposon origin.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 1–113 (full-length protein), likely generating antibodies that recognize multiple epitopes, which may provide robust detection in denaturing Western blot.
• For Western blot, consider optimizing the antibody dilution and ensure proper molecular weight markers around 13 kDa; validate band specificity using knockdown or knockout controls if available.
• Cross-reactivity with mouse and rat is indicated; however, sequence homology should be checked and appropriate tissue/cell lysates used for confirmation in your experimental system.
• In ELISA, the polyclonal nature may enhance sensitivity, but inclusion of recombinant protein standards and pre-immune serum controls is recommended.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research labs by providing validated raw materials like this anti-FAM127A/RTL8C antibody, which targets a retrotransposon-related protein candidate. As a dedicated B2B partner, we offer access to optimized antibody pairs, recombinant proteins, and ancillary reagents for IVD assay development, including rare and emerging targets. Whether you need bulk supply or custom sourcing, CamelBio bridges the gap from concept to clinic.