Anti-FABPI (I-FABP) Rabbit Monoclonal Antibody for WB, IF-P, IHC-P, ELISA - P12104

Core Product Specifications and Parameters

Biological Background: FABPI Function and Localization

• FABPI, also known as fatty acid-binding protein 2 (FABP2) or intestinal-type fatty acid-binding protein (I-FABP), is a lipid-binding protein primarily expressed in the intestine.
• It binds saturated long-chain fatty acids with high affinity and unsaturated long-chain fatty acids with lower affinity, playing a role in intracellular fatty acid transport and acyl-CoA ester trafficking.
• FABP2 is involved in triglyceride-rich lipoprotein synthesis and may function as a lipid sensor to help maintain energy homeostasis.
• The protein localizes to the cytoplasm and is highly expressed in the small intestine, particularly the jejunum, with lower levels in the large intestine.
• Post-translational modifications include acetylation, and its 3D structure has been resolved (reference proteome).

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1–100) of human FABPI, ensuring target specificity.
• For Western blot, expect a band at approximately 15 kDa; validate using intestinal tissue lysates, preferably from jejunum where expression is highest.
• Due to cross-reactivity with mouse and rat, this antibody may be suitable for comparative studies across species.
• For immunohistochemistry and immunofluorescence, optimize antigen retrieval and detection conditions appropriately.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and research teams with validated IVD raw materials, including this FABPI monoclonal antibody for intestinal and metabolic research. Our portfolio covers optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and custom sourcing, supporting your workflow from concept to clinic.