Anti-FABP3 Rabbit Polyclonal Antibody for WB, IF-P, IHC-P, ELISA - P05413

Core Product Specifications and Parameters

Biological Background: FABP3 Function and Localization

• FABP3, also known as heart-type fatty acid-binding protein (H-FABP) or mammary-derived growth inhibitor (MDGI), is a ~15kDa cytoplasmic protein.
• It belongs to the fatty acid-binding protein (FABP) family, which is involved in intracellular transport of long-chain fatty acids and their acyl-CoA esters.
• FABP3 is predominantly localized in the cytoplasm, consistent with its role in lipid trafficking.
• Post-translational modifications include acetylation and phosphorylation, which may regulate its activity.
• The protein has been identified through proteomics studies and direct protein sequencing.
• Its expression is high in heart, muscle, and mammary tissue, where it may influence lipid metabolism and cell growth regulation.

Experimental Guidance and Technical Tips

• The immunogen corresponds to full-length human FABP3 (aa 1-133), enabling recognition of both native and denatured protein forms.
• For Western blot, the predicted molecular weight is ~15kDa; use appropriate gel percentage and loading controls.
• For immunohistochemistry (IHC-P) and immunofluorescence (IF-P), consider antigen retrieval conditions and tissue fixation methods.
• Cross-reactivity with mouse is reported; validate in your specific sample system to ensure specificity.
• As a polyclonal antibody, background may vary; optimize blocking and detection conditions for each application.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for diagnostic manufacturers and researchers seeking high-quality IVD raw materials. Beyond this FABP3 polyclonal antibody, we offer validated antibody pairs, optimized monoclonal antibodies, and bulk ancillary reagents to support fatty acid-binding protein research and assay development. Our team also assists in sourcing rare targets and custom reagent production to accelerate your projects from concept to clinic.