Anti-ERMAP Rabbit Polyclonal Antibody for WB, ELISA - Q96PL5

Core Product Specifications and Parameters

Biological Background: ERMAP Function and Localization

• ERMAP is an erythroid membrane-associated protein that also functions as the Radin and Scianna blood group antigen (UniProt: Q96PL5).
• It may act as a cell-adhesion or receptor molecule in erythroid cells.
• The protein is predicted to localize to the cell membrane and cytoplasm.
• Tissue expression is mainly in erythroid-enriched bone marrow, with lower expression in leukocytes, thymus, lymph node, and spleen.
• ERMAP contains an immunoglobulin-like domain, a transmembrane helix, and a signal peptide, and is modified by glycosylation and phosphorylation.
• It is annotated with keywords such as Blood group antigen, Disulfide bond, Glycoprotein, Immunoglobulin domain, Membrane, Phosphoprotein.

Experimental Guidance and Technical Tips

• For Western blot, the antibody may detect a band around 53kDa. Validate in a relevant sample system, such as erythroid-enriched bone marrow lysates.
• For ELISA, consider using the recombinant immunogen fragment (amino acids 30-155) as a positive control.
• Cross-reactivity with mouse suggests potential use in mouse models; verify expression in the target tissue or cell line.
• This is a rabbit polyclonal antibody; use an appropriate anti-rabbit secondary antibody for detection.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting. This ERMAP antibody supports research in cell adhesion, erythroid biology, and blood group antigen studies. We offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing to streamline your development from concept to clinic.