Anti-EML2 Rabbit Polyclonal Antibody for WB and ELISA - O95834

Core Product Specifications and Parameters

Biological Background: EML2 Function and Localization

• EML2 (Echinoderm microtubule-associated protein-like 2) is a tubulin binding protein that inhibits microtubule nucleation and growth, leading to shorter microtubules.
• It belongs to the EMAP family and is also known as ELP70, EMAP2, and EMAP-2.
• Encoded by the EML2 gene (GeneID: 24139) in humans, the full-length protein has a predicted molecular weight of approximately 70.7 kDa (observed at 71 kDa).
• Subcellular localization is predominantly cytoplasmic, associated with the cytoskeleton and mitotic spindle.
• Contains WD repeat domains and coiled-coil regions, mediating protein-protein interactions.
• Exhibits ubiquitous tissue expression, suggesting fundamental roles in cellular architecture.
• Alternative splicing gives rise to multiple isoforms; annotated with keywords including 3D-structure, proteomics identification, and reference proteome.

Experimental Guidance and Technical Tips

• This polyclonal antibody was raised in rabbit against a recombinant fragment corresponding to amino acids 150–415 of human EML2; it is suitable for WB and ELISA applications.
• For WB, a band near the predicted 71 kDa is expected; validate in the relevant sample system and consider loading controls.
• Cross-reactivity with mouse EML2 is supported by the supplier; verify species-specific performance under your experimental conditions.
• In microtubule studies, combining this antibody with tubulin markers may help confirm subcellular localization.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and research laboratories one-stop access to IVD raw materials, including this anti-EML2 polyclonal antibody targeting a microtubule regulatory protein. Our supply capabilities encompass validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and rare-target sourcing—supporting cytoskeleton research and diagnostic development from concept to clinic.