Anti-ELMOD2 Polyclonal Antibody for WB, ELISA - Q8IZ81

Core Product Specifications and Parameters

Biological Background: ELMOD2 Function and Localization

• ELMOD2 (ELMO domain-containing protein 2) is encoded by the ELMOD2 gene and characterized as a GTPase-activating protein (GAP).
• It specifically activates Arf family GTPases ARL2, ARL3, ARF1, and ARF6, but not other Arf members, regulating intracellular trafficking and signaling.
• ELMOD2 plays a role in antiviral defense by modulating interferon (IFN)-related responses.
• At the protein level, ELMOD2 is detected in alveolar type II cells and alveolar macrophages, and its mRNA is broadly expressed across tissues including brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach, and testis.
• Functional keywords include GTPase activation, antiviral defense, and comprehensive proteomics identification.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1–130) of mouse ELMOD2, which shows high homology to human ELMOD2, supporting the observed cross-reactivity.
• For Western blot, expect a band around 35 kDa; consider using appropriate protein extraction and loading controls.
• For ELISA, this polyclonal antibody may be used as capture or detection reagent; pilot experiments are recommended to determine optimal concentrations.
• Verify specificity in knockout or knockdown models if available, as cross-reactivity with other ELMO domain proteins cannot be excluded.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides reliable one-stop access to IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. For researchers studying GTPase signaling, antiviral defense, or ELMOD2-related cellular processes, CamelBio streamlines procurement from discovery to clinical application. Contact us to discuss your specific needs for ELMOD2 or other rare targets.