Anti-ECHDC2 Rabbit Polyclonal Antibody for WB and ELISA - Q86YB7

Core Product Specifications and Parameters

Biological Background: ECHDC2 Function and Localization

• ECHDC2 (Enoyl-CoA hydratase domain-containing protein 2) is a mitochondrial protein encoded by the ECHDC2 gene, identified in the human reference proteome.
• Localizes to the mitochondrion, as evidenced by its transit peptide and proteomics-based subcellular localization data.
• Implicated in fatty acid and lipid metabolism, consistent with its enoyl-CoA hydratase domain and classification under the lyase enzyme class.
• The ECHDC2 gene undergoes alternative splicing, generating multiple transcript variants that may contribute to functional diversity.
• Subject to acetylation, a post-translational modification that can modulate enzymatic activity or protein stability within metabolic pathways.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant fusion protein spanning amino acids 1-292 of human ECHDC2 (NP_001185890.1). Validate this antibody in your target cell or tissue type to confirm specificity.
• Predicted molecular weight of ECHDC2 is 31 kDa; use appropriate molecular weight markers and loading controls in Western blotting.
• Tested applications include Western blot (WB) and ELISA. Optimize antibody dilution and blocking conditions for your specific assay format.
• Cross-reactivity with mouse and rat ECHDC2 has been reported; it is recommended to verify performance if using these species.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a streamlined procurement platform for IVD raw materials, including validated polyclonal antibodies like this anti-ECHDC2 antibody. Our inventory covers antibody pairs, bulk ancillary reagents, and rare-target sourcing to support lipid metabolism and mitochondrial research. Partner with CamelBio to efficiently bridge your raw material needs from concept to clinic.