Anti-DNAJC9 Polyclonal Antibody for WB, ELISA - Q8WXX5

Core Product Specifications and Parameters

Biological Background: DNAJC9 Function and Localization

• DNAJC9 (DnaJ homolog subfamily C member 9) is a dual-function histone chaperone and heat shock co-chaperone. Related references: PMID:33857403
• As a histone chaperone, it forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers, promoting nucleosome assembly. Related references: PMID:33857403
• It cooperates with TONSL and recruits histone chaperones ASF1A, NASP, and SPT2 to H3-H4 dimers. Related references: PMID:33857403
• Functions as a co-chaperone for HSP70 family proteins (HSPA1A, HSPA1B, HSPA8), potentially aiding in the recruitment of HSP70 machinery to histones. Related references: PMID:17182002, PMID:33857403
• Displays in vitro nucleosome assembly activity. Related references: PMID:33857403
• Subcellular localization: found in the nucleus, cytoplasm, and cell membrane.
• Tissue expression: detected in heart, placenta, liver, skeletal muscle, kidney, pancreas, thymus, ovary, colon, and peripheral blood.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal 260 amino acids, covering the majority of the protein; this may provide recognition of multiple epitopes.
• For WB, consider using appropriate loading controls and validate band size (~30 kDa) in relevant lysates.
• Based on cross-reactivity data, this antibody may detect DNAJC9 in human, mouse, and rat samples.
• ELISA applications may require optimization of coating antigen and antibody dilution.
• As a polyclonal antibody, batch-to-batch consistency should be verified for critical assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive portfolio of IVD raw materials, supporting diagnostic manufacturers and research teams from early-stage development to clinical application. This anti-DNAJC9 polyclonal antibody is part of our specialized collection for chaperone and epigenetics research, available for bulk procurement. Beyond antibodies, we provide validated antigen pairs, ancillary reagents, and custom sourcing for rare or emerging targets to accelerate your assay development pipeline.