Anti-DLX6 Polyclonal Antibody for WB, ELISA - P56179

Core Product Specifications and Parameters

Biological Background: DLX6 Function and Localization

• DLX6 (Homeobox protein DLX-6) is a member of the distal-less homeobox family of transcription factors, characterized by a conserved homeodomain that mediates sequence-specific DNA binding.
• It functions as a developmental protein, playing a critical role in embryonic patterning and organogenesis, particularly in craniofacial, limb, and brain development.
• The protein contains a nuclear localization signal and is predominantly found in the nucleus, consistent with its role as a transcriptional regulator.
• Multiple isoforms are produced by alternative splicing, potentially expanding its regulatory diversity.
• DLX6 is classified as a reference proteome protein, with robust proteomics identification evidence supporting its expression.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a region spanning amino acids 119-293, which covers part of the homeodomain and flanking sequences, likely providing specificity for DLX6.
• For Western blot, a band around 20 kDa is expected; consider using appropriate positive controls such as human embryonic or adult tissue lysates known to express DLX6.
• In ELISA, optimize antigen coating and antibody dilution conditions; cross-reactivity with other DLX family members should be evaluated if broader reactivity is a concern.
• Validate the antibody in your specific experimental system, as performance may vary with sample preparation and detection conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, laboratories, and research institutions streamlined access to IVD raw materials, including this DLX6 polyclonal antibody. As your one-stop partner, we supply validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and support rare target sourcing for developmental biology research. Let us bridge your concept-to-clinic journey with reliable raw-material solutions.