Anti-DLX2 Rabbit Polyclonal Antibody for WB, ELISA - Q07687

Core Product Specifications and Parameters

Biological Background: DLX2 Function and Localization

• DLX2 (Distal-less homeobox 2) is a homeobox transcription factor that acts as a transcriptional activator, e.g., of CGA/alpha-GSU via the downstream activin regulatory element (DARE) (By similarity).
• It plays a key role in the terminal differentiation of interneurons, including amacrine and bipolar cells in the developing retina, and in ventral forebrain development (By similarity).
• DLX2 likely contributes to craniofacial patterning and morphogenesis (By similarity).
• The protein localizes to the nucleus, consistent with its function as a DNA-binding transcription factor.
• DLX2 is subject to alternative splicing and phosphorylation, as indicated by UniProt keywords.
• Additional keywords include: Activator, Developmental protein, Differentiation, DNA-binding, Homeobox, Nucleus, Phosphoprotein, Reference proteome, Transcription, Transcription regulation.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-140) of human DLX2, which may confer specificity for this homeobox protein. Consider verifying antibody specificity using knockdown or knockout controls in relevant cell lines.
• This polyclonal antibody is suitable for WB; given the predicted molecular weight of 34 kDa, ensure appropriate gel percentage and transfer conditions. Validate in your sample system, as post-translational modifications (e.g., phosphorylation) may cause band shifts.
• For ELISA applications, optimize coating antigen and antibody dilution. Cross-reactivity with mouse and rat DLX2 allows for detection in rodent models; sequence homology should be checked to confirm epitope conservation.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with a comprehensive sourcing solution for IVD raw materials, including validated antibody pairs, bulk reagents, and rare-target antibodies like this anti-DLX2 polyclonal antibody. Committed to supporting neuroscience and developmental biology research, CamelBio offers reliable access to optimized antibodies, ancillary reagents, and customized sourcing services to accelerate your assay development from concept to clinic.