Anti-Cyclin B2 Polyclonal Antibody for WB, ELISA - O95067

Core Product Specifications and Parameters

Biological Background: Cyclin B2 Function and Localization

• Cyclin B2 is a member of the cyclin family, specifically a G2/mitotic-specific cyclin that accumulates during the cell cycle and promotes entry into mitosis.
• It plays an essential role in the control of the cell cycle at the G2/M (mitosis) transition, likely by forming a complex with cyclin-dependent kinase 1 (CDK1) to drive mitotic progression.
• Cyclin B2 is a phosphoprotein; its activity is regulated by phosphorylation events that control its degradation and subcellular localization during cell division.
• The protein is proteomically identified and part of the reference proteome, indicating its well-characterized role in human biology.

Experimental Guidance and Technical Tips

• The immunogen covers the N-terminal region of human Cyclin B2, which may be conserved across species; verify reactivity in your sample system.
• For Western blotting, a band around 45kDa is expected under reducing conditions; include appropriate molecular weight markers and loading controls.
• For ELISA, the polyclonal nature may provide sensitive detection; validate with recombinant protein or cell lysates to confirm specificity.
• Polyclonal antibodies may exhibit lot-to-lot variability; incorporate positive and negative controls in each experiment.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for IVD raw materials, offering access to high-quality antibodies like this anti-Cyclin B2 polyclonal antibody. Whether you need bulk reagents, matched antibody pairs, or support in securing rare-target raw materials, CamelBio bridges the gap from concept to clinic.