Anti-CSRNP1 Rabbit Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q96S65

Core Product Specifications and Parameters

Biological Background: CSRNP1 Function and Localization

• CSRNP1, also known as AXUD1, URAX1, and TAIP-3, is a cysteine/serine-rich nuclear protein encoded by the CSRNP1 gene in humans.
• It functions as a transcriptional activator that binds to the consensus DNA sequence 5'-AGAGTG-3' (By similarity).
• CSRNP1 may have a tumor-suppressor role and is implicated in apoptosis regulation.
• The protein is predominantly localized to the nucleus, consistent with its role in transcription regulation.
• Ubiquitously expressed, with highest levels in lung, placenta, skeletal muscle, pancreas, and leukocytes; frequently down-regulated in various cancers.
• Functional keywords include: Activator, Apoptosis, DNA-binding, Nucleus, Transcription, Transcription regulation.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-200) of human CSRNP1, which may recognize full-length and any N-terminal isoforms. Validate specificity by knockdown or knockout controls.
• Recommended for Western blot (WB) at dilutions to be optimized; expect a band around 64 kDa. For immunohistochemistry (IHC-P) and immunofluorescence (IF/ICC), include appropriate antigen retrieval and permeabilization steps.
• Cross-reactivity with mouse and rat is reported; performance should be verified in these species' tissues or cell lines due to possible sequence differences.
• For ELISA applications, consider pairing with a validated capture/detection antibody and assay conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and researchers with reliable access to IVD raw materials, including validated antibodies for apoptosis and transcription factor research. We offer one-stop sourcing for antibody pairs, monoclonal and polyclonal antibodies, and ancillary reagents to streamline your assay development. With a focus on rare and emerging targets like CSRNP1, we connect you from concept to clinic with technical and supply chain support.