Anti-CSNK1G3 Polyclonal Antibody for WB, ELISA - Q9Y6M4

Core Product Specifications and Parameters

Biological Background: CSNK1G3 Function and Localization

• CSNK1G3 is a serine/threonine-protein kinase that preferentially phosphorylates acidic substrates such as caseins, acting as a key regulator in multiple signaling cascades.
• It plays a critical role in the Wnt signaling pathway, modulating downstream transcriptional responses.
• CSNK1G3 contributes to the regulation of fast synaptic transmission via glutamate receptor modulation (by similarity).
• The protein is localized in the cytoplasm, consistent with its role in intracellular signal transduction.
• Post-translational modifications include acetylation and phosphorylation, which may influence its kinase activity and interaction networks.
• As a member of the casein kinase 1 family, CSNK1G3 shares structural and functional similarities with other CK1 isoforms involved in diverse cellular processes.

Experimental Guidance and Technical Tips

• This antibody is recommended for use in Western blot (WB) and ELISA applications as indicated; optimal dilutions should be determined empirically.
• The immunogen corresponds to a recombinant fragment comprising amino acids 304-423, which may influence isoform recognition; validation in the relevant sample system is advised.
• Cross-reactivity with mouse and rat orthologs has been observed; consider performing species-specific control experiments to confirm detection specificity.
• For WB, the predicted molecular weight is 51 kDa; ensure appropriate gel percentage and transfer conditions for accurate band detection.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with reliable access to high-quality IVD raw materials, including validated antibody pairs, optimized polyclonal and monoclonal antibodies, and bulk ancillary reagents. This anti-CSNK1G3 antibody supports researchers targeting casein kinase I gamma-3 in Wnt signaling, kinase studies, and neurobiology. Backed by our extensive sourcing network, we offer one-stop procurement solutions for even rare target raw materials, helping streamline your development from concept to clinic.