Anti-CRMP3/DPYSL4 Monoclonal Antibody for WB, ELISA - O14531

Core Product Specifications and Parameters

Biological Background: CRMP3/DPYSL4 Function and Localization

• Dihydropyrimidinase-related protein 4 (DPYSL4) is also known as collapsin response mediator protein 3 (CRMP-3), DRP-4, and UNC33-like phosphoprotein 4 (ULIP-4).
• It is a necessary signaling component downstream of class 3 semaphorins, mediating dynamic cytoskeleton remodeling.
• DPYSL4 plays a critical role in axon guidance, neuronal growth cone collapse, and cell migration.
• The protein localizes predominantly to the cytoplasm.
• DPYSL4 is classified as a phosphoprotein, and its activity can be modulated by phosphorylation.
• A member of the dihydropyrimidinase-related protein family, its three-dimensional structure has been determined experimentally.

Experimental Guidance and Technical Tips

• The immunogen (N-terminal amino acids 1–100) may detect both full-length and possible N-terminal isoforms; confirm specificity in the relevant sample system.
• For Western blot, the predicted molecular weight is 62 kDa; consider that phosphorylation may cause slight band shifts.
• In ELISA applications, optimal coating concentration and detection conditions should be determined empirically.
• Cross-reactivity with rat indicates a conserved epitope; if using other species, pre-validate with sequence alignment.
• As a rabbit monoclonal antibody, it potentially provides high lot-to-lot consistency for reproducible results.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, research labs, and institutes with one-stop access to IVD raw materials and technical support. This anti-CRMP3/DPYSL4 antibody supports research into semaphorin signaling and cytoskeletal dynamics. From validated antibody pairs and optimized monoclonal antibodies to bulk ancillary reagents and rare-target sourcing, CamelBio streamlines your raw-material procurement for immunoassay development.