Anti-CPNE3 Polyclonal Antibody for WB and ELISA - O75131

Core Product Specifications and Parameters

Biological Background: CPNE3 Function and Localization

• CPNE3 (Copine III) is a calcium-dependent phospholipid-binding protein encoded by the CPNE3 gene.
• It plays a role in ERBB2-mediated tumor cell migration in response to heregulin stimulation. Related references: PMID:20010870
• Subcellular localization includes the nucleus, cytoplasm, cell membrane, and focal adhesions.
• Widely expressed, with notable levels in breast, prostate, ovarian tissues, and neutrophils.
• CPNE3 contains repeat domains and is identified as a phosphoprotein.
• Functions in signaling pathways that regulate cell adhesion and migration.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 238-537 of human CPNE3; this region may enable detection of full-length CPNE3 in Western blotting.
• Cross-reactivity with mouse CPNE3 has been observed; consider validating in mouse cell or tissue lysates for your specific experimental system.
• For ELISA, optimize the coating antigen concentration and antibody dilution to suit your assay sensitivity requirements.
• Standard blocking and washing conditions for rabbit polyclonal antibodies are recommended as a starting point.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with one-stop access to IVD raw materials, including validated polyclonal antibodies like this anti-CPNE3 antibody for oncology and cell signaling research. Our portfolio encompasses optimized antibody pairs, recombinant proteins, and bulk ancillary reagents to support your assay development and production needs. For rare or custom targets, CamelBio offers tailored sourcing solutions to accelerate your project from concept to clinic.