Anti-COR28 Polyclonal Antibody for WB and ELISA - Q8L983

Core Product Specifications and Parameters

Biological Background: COR28 Function and Localization

• Encoded by the COR28 gene, cold-regulated protein 28 is a nuclear protein involved in central circadian clock regulation and flowering time promotion.
• Together with COR27, binds to chromatin of clock-associated evening genes (TOC1, PRR5, ELF4) and cold-responsive genes to repress their transcription, thereby promoting flowering. Related references: PMID:27837007 PMID:27990760
• Functions as a negative regulator of freezing tolerance, linking cold stress responses with circadian rhythms. Related references: PMID:27837007 PMID:27990760
• Localizes exclusively to the nucleus, consistent with its role as a transcriptional repressor.
• Classified under keywords: Biological rhythms, Nucleus, Reference proteome, Repressor, Transcription, Transcription regulation.

Experimental Guidance and Technical Tips

• The immunogen (recombinant protein covering amino acids 50–170) targets a central region; consider this when designing complementary detection reagents or mapping epitopes.
• Optimize antibody dilution and blocking conditions for Western blot in Arabidopsis thaliana lysates, as cross-reactivity with other species is not expected.
• For ELISA, consider pairing with a validated detection antibody to achieve sensitive quantification of COR28 in plant extracts.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers comprehensive access to IVD raw materials, including validated polyclonal and monoclonal antibodies, bulk ancillary reagents, and customized sourcing for rare targets. This anti-COR28 antibody supports plant circadian biology, flowering time, and cold stress research, and is available with flexible supply options to meet your development and manufacturing needs.