Anti-COG7 Rabbit Polyclonal Antibody for IF/ICC, ELISA - P83436

Core Product Specifications and Parameters

Biological Background: COG7 Function and Localization

• COG7 (Conserved oligomeric Golgi complex subunit 7), also known as Component of oligomeric Golgi complex 7 (CDG2E), is a subunit of the conserved oligomeric Golgi (COG) complex.
• It is required for normal Golgi function, playing a role in protein transport and glycosylation processes.
• Localized to the Golgi apparatus membrane.
• Encoded by the COG7 gene in humans (Gene ID: 91949), mutations are associated with congenital disorder of glycosylation type IIe (CDG2E).
• Keywords associated with COG7 include Golgi apparatus, membrane, protein transport, transport, and congenital disorder of glycosylation.
• The protein has a molecular weight of approximately 86 kDa.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 511–770 (NP_705831.1), suggesting the antibody recognizes a C‑terminal region of human COG7.
• For immunofluorescence (IF/ICC), permeabilization is recommended; fixation conditions may need optimization for Golgi membrane targets.
• In ELISA, the recombinant protein or peptide encompassing the immunogen sequence may be used for direct coating or competition assays.
• Validate the antibody in the relevant sample system (e.g., human cell lines or tissues) and include appropriate controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. For COG7 and other Golgi-associated targets, we supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and support rare target raw-material sourcing. Please contact us to discuss your specific procurement needs.