Anti-CNPY2 Polyclonal Antibody for WB, IHC-P, ELISA - Q9Y2B0

Core Product Specifications and Parameters

Biological Background: CNPY2 Function and Localization

• Protein canopy homolog 2 (CNPY2), also known as MSAP, TMEM4, and Zsig9, is a 20652 Da protein that exists in alternatively spliced isoforms and contains a signal peptide and disulfide bonds.
• CNPY2 acts as a positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC); it prevents MIR-mediated ubiquitination and subsequent proteasomal degradation of MRLC.
• The protein localizes to the endoplasmic reticulum, consistent with its role in protein processing and secretion.
• CNPY2 is widely expressed, with highest levels detected in adult placenta, liver, and pancreas.
• Post-translational modifications include phosphorylation, as indicated by the Phosphoprotein keyword, which may regulate its activity or localization.
• Functional keywords such as Alternative splicing, Disulfide bond, Endoplasmic reticulum, and Signal highlight its structural and trafficking features.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the full-length mature protein (amino acids 1–182), so the antibody likely recognizes endogenous CNPY2 across multiple isoforms. For WB, expect a band around 21 kDa (or possibly 18–21 kDa depending on cleavage).
• For IHC-P, consider antigen retrieval conditions and validate in tissues with known expression, such as placenta, liver, or pancreas.
• This antibody can be used in ELISA for protein quantification; titrate appropriately for your specific assay format.
• Given its role in neurite outgrowth, consider using neuronal cell lines or primary neurons to study CNPY2 function; validate specificity with knockdown controls.

CamelBio: Your One-Stop Sourcing Bridge

As a leading IVD raw material provider, CamelBio supports diagnostic manufacturers and research labs with high-quality antibodies like this CNPY2 rabbit polyclonal antibody. Whether you need validated antibody pairs, bulk reagents, or assistance sourcing rare target materials, we offer end-to-end solutions for neuroscience and cell biology research applications. Partner with us to streamline your assay development from concept to clinic.