Anti-CGB7 Rabbit Polyclonal Antibody for WB, ELISA - P0DN87

Core Product Specifications and Parameters

Biological Background: CGB7 Function and Localization

• CGB7 encodes the beta subunit of human chorionic gonadotropin (hCG), a glycoprotein hormone essential for pregnancy maintenance and maternal adaptation.
• hCG is composed of a common alpha subunit (shared with LH, FSH, TSH) and a unique beta subunit that confers receptor specificity and biological activity.
• The beta subunit stimulates ovarian steroidogenesis, particularly progesterone production, to support early pregnancy.
• CGB7 is highly and specifically expressed in the placenta throughout gestation.
• The protein is secreted and undergoes post-translational modifications including glycosylation and disulfide bond formation.
• Calculated molecular weight is approximately 18 kDa, consistent with the observed band in Western blot.

Experimental Guidance and Technical Tips

• The immunogen (amino acids 21–165) encompasses nearly the entire mature CGB7 protein; the polyclonal antibody likely recognizes multiple epitopes and may detect both reduced and non-reduced forms.
• For Western blot, consider using placental tissue lysates or hCG-expressing cell lines (e.g., JEG-3) as positive controls; validate the ~18 kDa band.
• Reported cross-reactivity with mouse and rat should be confirmed in your experimental system, as sequence homology may vary.
• In ELISA, the polyclonal antibody can be used for capture or detection; titrate and test paired with monoclonal antibodies for sandwich assay development.
• As with any polyclonal reagent, verify lot-to-lot consistency and consider affinity purification for critical applications.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers and laboratories a streamlined supply chain for IVD raw materials. This anti-CGB7 polyclonal antibody supports reproductive biology research and pregnancy-related immunoassay development. Explore our catalog for validated antibody pairs, bulk reagents, and customized sourcing solutions to accelerate your diagnostic pipeline.