Anti-CDYL2 Rabbit Polyclonal Antibody for WB, ELISA - Q8N8U2

Core Product Specifications and Parameters

Biological Background: CDYL2 Function and Localization

• CDYL2, also known as PCCP1, is a nuclear protein containing a chromodomain, a structural motif frequently associated with chromatin binding and epigenetic regulation.
• It is encoded by the CDYL2 gene (GeneID: 124359) and classified as a reference proteome member, indicating its importance in the human proteome.
• Subcellularly, CDYL2 is localized to the nucleus, as evidenced by experimental annotations.
• The protein is ubiquitously expressed in human tissues, pointing to a wide-ranging role in nuclear processes.
• The molecular weight of CDYL2 is approximately 57 kDa, and its three-dimensional structure has been experimentally determined (3D-structure keyword).
• CDYL2 has been detected in large-scale proteomic analyses, confirming protein-level expression.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein corresponding to amino acids 60-230 of human CDYL2. For Western blot, the predicted band size is around 57 kDa, but post-translational modifications may cause shifts; consider running appropriate molecular weight markers.
• This antibody is suitable for WB and ELISA. For WB, start with a standard dilution (e.g., 1:500-1:2000) and optimize for your specific sample and detection system. For ELISA, use recombinant CDYL2 protein as a reference standard to validate performance.
• Cross-reactivity with mouse and rat has been observed; when using these species, verify expected band patterns due to potential sequence homology.
• Given the nuclear localization, consider using nuclear extraction protocols to enrich the target protein for improved detection.

CamelBio: Your One-Stop Sourcing Bridge

• CamelBio is your dedicated partner in IVD raw material sourcing, offering a comprehensive range of antibodies, antigens, and ancillary reagents to support diagnostic development and research. With this CDYL2 antibody, we provide a reliable tool for investigating chromatin biology and epigenetic mechanisms. Our supply capabilities include validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk reagents, and custom sourcing for rare targets, ensuring a seamless procurement experience from concept to clinic.