Anti-CDX4 Polyclonal Antibody for WB, ELISA - O14627

Core Product Specifications and Parameters

Biological Background: CDX4 Function and Localization

• CDX4 (Caudal-type homeobox protein 4) is a member of the caudal-related homeobox family of transcription factors.
• It contains a homeobox DNA-binding domain, enabling sequence-specific DNA interaction and gene regulation.
• CDX4 localizes to the nucleus, consistent with its role as a transcriptional regulator.
• The protein is classified as a developmental protein, likely involved in embryonic patterning and anterior-posterior axis specification.
• CDX4 functions in transcriptional regulation, modulating the expression of downstream target genes.
• As a homeobox protein, it binds to regulatory DNA sequences and may contribute to chromatin remodeling during development.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 1–170 of human CDX4, encompassing the N-terminal region necessary for native protein recognition; verify specificity in your model system.
• For Western blot, the predicted molecular weight is approximately 30 kDa. Consider using nuclear extracts to enrich CDX4 and optimize detection.
• In ELISA applications, titrate the antibody against recombinant CDX4 or CDX4-expressing cell lysates to determine the optimal working concentration.
• Cross-reactivity with mouse CDX4 is reported; validate staining patterns in relevant tissue sections or cell lines if using mouse models.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your integrated partner for IVD raw-material procurement, supporting diagnostic manufacturers with validated antibodies, bulk ancillary reagents, and specialized sourcing for rare targets. This anti-CDX4 polyclonal antibody supports research in developmental biology and gene regulation, and we can assist in scaling supply, customizing antibody pairs, or fulfilling custom production needs. Contact CamelBio to streamline your development pipeline from concept to clinic.