Anti-CDH8 Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - P55286

Core Product Specifications and Parameters

Biological Background: Cadherin-8 Function and Localization

• Cadherin-8 (CDH8) is a member of the cadherin superfamily, which are calcium-dependent cell adhesion proteins.
• It mediates homophilic cell-cell adhesion, contributing to the sorting of heterogeneous cell types.
• CDH8 is a single-pass type I membrane protein localized to the cell membrane.
• Mainly expressed in the brain, including nerve cell lines such as retinoblasts, glioma cells, and neuroblasts.
• Contains cadherin repeat domains and requires calcium binding for its adhesive function.
• Classified under keywords: Calcium, Cell adhesion, Glycoprotein, Phosphoprotein, Transmembrane.

Experimental Guidance and Technical Tips

• As a rabbit polyclonal antibody raised against recombinant human CDH8, it may exhibit reactivity with mouse and rat, but validation in the relevant sample system is recommended.
• For Western blot, consider using whole brain lysates or neural cell lines.
• For IF/ICC, optimize permeabilization and fixation conditions for membrane protein detection.
• ELISA may be used for quantification or screening, with appropriate controls essential for reliable results.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and researchers with a one-stop sourcing solution for IVD raw materials. For cadherin-8 (CDH8) research, we offer validated antibody pairs, monoclonal/polyclonal antibodies, and bulk ancillary reagents to streamline your assay development. Whether you need rare target raw materials or technical consulting, CamelBio supports your project from concept to clinic.