Anti-CDC42EP3 Rabbit Polyclonal Antibody for WB and ELISA - Q9UKI2

Core Product Specifications and Parameters

Biological Background: CDC42EP3 Function and Localization

• CDC42EP3, also known as Binder of Rho GTPases 2 (BORG2) or CDC42 effector protein 3, belongs to the Cdc42 effector protein family.
• It is probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly and cell shape changes.
• CDC42EP3 can induce pseudopodia formation in fibroblasts, suggesting a role in cell migration and morphology.
• The protein is found in the endomembrane system, cytoplasm, and cytoskeleton, indicating dynamic intracellular localization.
• Highly expressed in the heart and weakly in the brain, pointing to potential tissue-specific functions.
• Keywords include cell shape, cytoskeleton, membrane, and phosphoprotein, highlighting its involvement in phosphorylation-mediated signaling.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the near full-length human CDC42EP3 (amino acids 1-254). For Western blot, expect a band around 28 kDa in human, mouse, and rat lysates.
• In ELISA, consider that the polyclonal antibody may detect native and denatured forms; optimization of coating antigen and buffer conditions is recommended.
• Validate the antibody in your specific experimental system, as expression levels and subcellular localization may vary with tissue type and cell context.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop partner for IVD raw materials, offering validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents to streamline your development pipeline. For research on actin cytoskeleton dynamics and cell shape regulation, we provide reliable sourcing of CDC42EP3 antibodies and related cytoskeletal targets. Our team also excels in rare target raw-material procurement, helping you accelerate from concept to clinic with confidence.