Anti-CD90/Thy1 Monoclonal Antibody for FC - P04216

Core Product Specifications and Parameters

Biological Background: CD90/Thy1 Function and Localization

• CD90 (Thy-1) is a 18 kDa GPI-anchored membrane glycoprotein belonging to the immunoglobulin superfamily.
• Encoded by the THY1 gene (GeneID: 7070), the protein is also known as CDw90 and Thy-1 antigen.
• Functionally, CD90 may participate in cell-cell or cell-ligand interactions during synaptogenesis and other brain-related events.
• It is localized on the cell membrane, anchored via a GPI (glycosylphosphatidylinositol) moiety, with no transmembrane domain.
• Post-translational modifications include N-linked glycosylation, disulfide bond formation, phosphorylation, and a pyrrolidone carboxylic acid modification at the N-terminus.
• The protein contains an immunoglobulin-like domain, characteristic of adhesion and signaling molecules.
• As a reference proteome member, CD90 has been extensively identified in proteomics studies.

Experimental Guidance and Technical Tips

• The immunogen covers the extracellular region (amino acids 20-130), making this antibody suitable for detecting cell surface CD90 by flow cytometry.
• For FC assays, use live, unfixed cells whenever possible to maintain epitope integrity; titrate the antibody to determine the optimal concentration.
• Consider appropriate controls, including isotype controls and CD90-negative cell lines or knockout models, to distinguish specific staining.
• The APC conjugate allows for direct detection without secondary reagents; ensure the detector settings of your flow cytometer are compatible with APC emission.
• This antibody is cross-reactive with human CD90; validate in your specific sample system to confirm performance.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, research institutes, and laboratories with one-stop access to IVD raw materials, supporting every stage from concept to clinic. This anti-CD90 monoclonal antibody serves immunology and neuroscience research applications; CamelBio can supply validated antibody pairs, bulk amounts, ancillary reagents, and assist with rare target raw-material sourcing. Partner with CamelBio to streamline your diagnostic development with reliable, high-quality antibody products.