Anti-CD45RB Rabbit Polyclonal Antibody for WB, IF, ELISA - P08575-9

Core Product Specifications and Parameters

Biological Background: CD45RB Function and Localization

• CD45RB (Isoform 7 of Receptor-type tyrosine-protein phosphatase C) is a transmembrane protein tyrosine phosphatase also known as Leukocyte common antigen (L-CA) and T200.
• It is encoded by the PTPRC (CD45) gene in humans (Gene ID: 5788).
• The isoform has a calculated molecular weight of approximately 135.7 kDa.
• As a member of the protein tyrosine phosphatase family, it functions as a receptor-type phosphatase, likely involved in dephosphorylating tyrosine residues in signaling pathways.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the extracellular region (amino acids 26–463) of human CD45RB; the antibody likely targets an extracellular epitope.
• For western blotting, the predicted band size is ~135 kDa; consider using 8 % SDS-PAGE and adequate transfer times.
• Cross-reactivity with mouse and rat has been observed; validate the antibody’s performance in your specific model system if species other than human are used.
• For immunofluorescence applications, standard fixation and permeabilization may be required; optimize conditions based on cellular localization of the target.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated IVD raw‑material partner, offering validated antibody pairs, optimized polyclonal antibodies like this CD45RB Rabbit pAb, and bulk ancillary reagents. For researchers and manufacturers targeting leukocyte markers or immune‑cell profiling, CamelBio provides reliable procurement solutions and rare‑target sourcing support to accelerate assay development from concept to clinic.